Dr. Tsoi has strong interests in investigating the pathology and genetic architecture of complex cutaneous disorders using systems biology approaches, and his work focused on developing data integration approaches to enhance prioritization and interpretation of high throughput experimental results. He joined the Department of Dermatology, Department of Computational Medicine & Bioinformatics, and the Department of Biostatistics at the University of Michigan in 2015-2016 as a faculty. Working with Drs. James T. Elder and Johann E Gudjonsson, Dr. Tsoi’s research aims to develop analysis pipelines and computational approaches to provide biological inferences from genetics and genomics data. His work in genetic association studies revealed over 30 novel psoriasis susceptibility regions, and highlighted different disease pathways. He also led the analysis and developed computational pipeline to study psoriasis transcriptomes, and his work uncovered over 1,000 novel transcripts in skin.